Thymopeptide, dzina la mankhwala akumadzulo.Mafomu odziwika bwino amaphatikizapo mapiritsi okhala ndi enteric, makapisozi okhala ndi enteric, ndi jakisoni.Ndi immunomodulatory mankhwala.Amagwiritsidwa ntchito kwa odwala omwe ali ndi matenda a chiwindi a B;matenda osiyanasiyana oyambirira kapena achiwiri a T-cell;matenda ena a autoimmune;matenda osiyanasiyana a chitetezo chamthupi;adjuvant chithandizo cha zotupa.
Contraindication
1, Ndi contraindicated kwa iwo amene matupi awo sagwirizana ndi mankhwala kapena limba transplantation.
2, hyperfunction ya chitetezo cham'manja ndiyoletsedwa.
3, Thymus hyperfunction ndiyoletsedwa.
Kusamalitsa
Mapiritsi a thymopeptide okhala ndi enteric, makapisozi okhala ndi thymopeptide:
1. mankhwalawa amagwira ntchito yochizira popititsa patsogolo chitetezo cha mthupi cha wodwalayo, choncho sayenera kugwiritsidwa ntchito kwa odwala omwe akudwala immunosuppressive therapy (mwachitsanzo, olandira limba), pokhapokha ngati ubwino wa chithandizo umaposa zoopsa zake.
2. Chiwindi chimayenera kuyang'aniridwa nthawi zonse panthawi ya chithandizo.
3. Odwala osakwanitsa zaka 18 ayenera kutsatira malangizo achipatala.
4. Mankhwalawa amapangidwa kuti azigwiritsidwa ntchito ngati mankhwala owonjezera.
5.Siyani mankhwalawa pamene zizindikiro monga zotupa pakhungu zimawonekera.
Thymopeptide ya jakisoni, Thymopeptide jekeseni:
1. Ndi zoletsedwa kwa iwo amene sagwirizana ndi zosakaniza zomwe zili mu mankhwalawa, ndipo ziyenera kugwiritsidwa ntchito mosamala kwa omwe ali ndi matupi awo sagwirizana.Kwa anthu omwe sali pakhungu, kuyezetsa kwa intradermal sensitivity (kukonzekera 25μg/ml yankho ndikubaya 0.1ml intradermally) kuyenera kuchitidwa musanabadwe jekeseni kapena mutatha kulandira chithandizo, ndipo ndizoletsedwa kwa omwe ali ndi vuto.
2.Ngati pali kusintha kulikonse kwachilendo monga turbidity kapena flocculent precipitate, kugwiritsa ntchito mankhwalawa ndikoletsedwa.
Zotsatira za Pharmacological
Mankhwalawa ndi mankhwala a immunomodulating, omwe ali ndi ntchito yolamulira ndi kupititsa patsogolo chitetezo cha mthupi cha maselo aumunthu, amatha kulimbikitsa kusasitsa kwa maselo a T, amatha kulimbikitsa kusasitsa kwa T lymphocytes m'magazi ozungulira pambuyo pa kutsegula kwa mitogens, kuonjezera katulutsidwe. a lymphokines osiyanasiyana (mwachitsanzo, α, γ interferon, interleukin 2, ndi interleukin 3) ndi T maselo pambuyo kutsegula kwa ma antigen kapena mitogens osiyanasiyana, ndi kuonjezera mlingo wa lymphokine cholandilira pa T maselo.Imawonjezeranso mayankho a lymphocyte kudzera pakuyambitsa kwake pama cell othandizira a T4.Komanso, mankhwalawa angakhudze chemotaxis wa NK kalambulabwalo maselo, amene amakhala cytotoxic pambuyo kukhudzana ndi interferon.Komanso, mankhwalawa amatha kumapangitsanso kukana kwa thupi ku ma radiation komanso kusintha komanso kupititsa patsogolo chitetezo chamthupi chamthupi.
Nthawi yotumiza: Jun-03-2019