Manufactory Supply 114471-18-0 Nesiritide Acetate (BNP-32)99% ufa woyera CAS NO.114471-18-0
Mafotokozedwe Akatundu
Nesiritide Acetate (BNP-32) CAS NO: 114471-18-0
Nesiritide ndi brainnatriureticpeptide (BNChemicalbookP) yopangidwa kuchokera ku Escherichiacoli pogwiritsa ntchito ukadaulo wa DNA wophatikizanso, ndipo zotsatira zake zimakhala zofanana kwambiri ndi za BNP yamunthu.Lili ndi 32-amino acid polypeptide, yomwe imalumikizidwa ndi mgwirizano wa disulfide pakati pa L0 ndi 26th amino acid (onse a cysteine), kupanga mphete yokhala ndi l7 amino acid.
Nesiritide imagwira ntchito pambuyo pomanga ma natriuretic peptide A ndi B receptors.Kuphatikiza pakuwonjezera kupanga cGMP, nesilitide idachepetsanso ntchito ya renin-angiotensin system (RAS) ndi mitsempha yachifundo.Lili ndi mphamvu yowonjezereka ya thupi lonse la arteriole ndi venule.Ikhoza kuchepetsa kwambiri pulmonary capillary chock pressure ndi Chemicalbook right atry pressure J, ndi kuchepetsa kudzaza kwa mtima mu mtima kulephera.Nesiritide imathanso kuchepetsa kukana kwathunthu kwa mitsempha yam'mitsempha, kuti muchepetse kuthamanga kwa mtima pakulephera kwa mtima.Ikhoza kuonjezera chiwerengero cha mtima, ndipo njira yake ikugwirizana ndi kuchepetsa kutsika kwa mtima.Imakhala ndi dilating kwenikweni pama coronary artery.Zimakhalanso ndi zotsatira zochepetsera kugwiritsa ntchito mpweya wa myocardial.
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Takhazikitsa ubale wamabizinesi ochezeka ndi mazana amakasitomala ochokera kumaiko ndi zigawo zopitilira 50.Gulu lathu ladzipereka kupatsa makasitomala zinthu zabwino kwambiri pamitengo yabwino komanso ntchito yabwino.Kwa zaka zambiri, kampani yathu yapambana kukhulupiriridwa ndi kukondedwa ndi makasitomala athu ndi zinthu zapamwamba, ntchito zapamwamba, komanso mitengo yampikisano.
Tidzapanga njira yabwino kwambiri komanso yokhazikika yoperekera makasitomala, kutsatira mzimu wotumikira makasitomala, kudalira ndalama zolimba ndi mbiri yabwino ya mgwirizano mumakampani, kupereka makasitomala zinthu zapamwamba ndi ntchito.Panthawi imodzimodziyo, ndife okonzeka kulimbikitsa kusinthanitsa ndi mgwirizano wowona mtima ndi amalonda apakhomo ndi akunja kuti apange tsogolo labwino pamodzi.Ndiwokupatsirani wabwino kwambiri.
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